World’s first robotic surgery to remove kidney cancer extending into the heart

World’s first robotic surgery to remove kidney cancer extending into the heart

The surgical team used 3-D animation to properly strategize the procedure. (c) Keck Medicine of USC

A surgical team at Keck Medicine of the University of Southern California (USC) has pushed the boundaries of clinical care by performing the first-ever robotic, minimally-invasive surgical removal of a stage IV tumor thrombus, which is when a kidney cancer tumor extends into the heart. The nearly 10-hour procedure required painstaking precision from three renowned surgeons, a critical-care anesthesiologist and a radiologist. In doing so, they reduced the patient’s risk of sudden death from the tumor breaking off into the heart and lungs.

Typically, the surgery for a stage IV tumor thrombus is both traumatic and risky. It requires major open surgery, wherein the patient’s chest and abdomen are opened completely, while the anesthesiologist monitors the patient and the tumor thrombus closely. The goal is to remove the tumor and thrombus from the inferior vena cava and the heart, while ensuring it does not break. Several quarts of blood are needed for transfusion and patients have a one in 20 chance of expiring during the procedure.

The use of robotic surgery techniques significantly reduced trauma to the patient and minimized blood loss by more than five-fold. By using small incisions, the patient’s hospital stay was only six days, as opposed to two to three weeks, which is typical after open surgery. Overall recovery time was also reduced significantly. Such multi-disciplinary collaboration lays the groundwork for using advanced technology to build higher standards of patient care, even in the most complex cases.

“This exciting feat promises to redefine the boundaries of what is surgically possible through skill, collaboration and technology,” said Inderbir S. Gill, MD, distinguished professor of urology, founding executive director of the USC Institute of Urology and the associate dean of clinical innovation at the Keck School of Medicine of USC. Gill led the multidisciplinary team that performed the surgery. “Our hope is that we can now propel the field at large to turn such futuristic robotic surgery into our present standard-of-care.”

Physicians at Keck Medicine are accustomed to providing highly specialized care. As a tertiary and quarternary care medical center, Keck Medicine accepts a high volume of complex cases. However, because it is an academic medical center with some of the top physician-researchers in the country, Keck Medicine has the collective brainpower, skill-set and resources to tackle such advanced cases.

Prior to the surgery, Vinay Duddalwar, MD, associate professor of clinical radiology, created three-dimensional animated maps of the patient’s chest and abdomen so that surgeons could pre-plan their entire surgical strategy with extreme, millimeter precision. The procedure began with Namir Katkhouda, MD, PhD, professor of surgery, who performed a surgical maneuver to control blood flow to the patient’s liver. Next, Gill used the latest-generation Xi da Vinci surgical robot to completely dissect the tumor-bearing kidney through small keyhole incisions in the patient’s abdomen to control various blood vessels, which allowed him access around and into the inferior vena cava where the cancer had spread.

Then, Mark Cunningham, MD, associate professor of surgery, put the patient on a heart-lung bypass machine to create a bloodless environment for tumor removal. He opened the patient’s heart using a minimally invasive incision through the ribcage. Cunningham and Gill then worked quickly, efficiently and simultaneously from the chest and abdomen to remove the tumor thrombus from the heart and inferior vena cava, respectively, with Cunningham working from the chest downward and Gill working from the abdomen upward. All the while Duraiyah Thangathurai, MD, professor of clinical anesthesiology and chief of critical care medicine, monitored the patient’s organ function, keeping a close eye on the patient’s heart using an esophageal echo probe. If a portion of the tumor were to break off into the heart or lungs, the patient would die instantly. “We are proud of our ability to coordinate such complex efforts between the cardiac and urologic surgical teams with skill and dexterity,” said Cunningham. “This was the driver of our success and exactly the standard we strive for across the institution.”

Source: Keck Medicine of USC