Out with the old and in with the new – there is a steady coming and going of fluid called aqueous humor in human eyes. But intraocular pressure rises if the amount of newly produced aqueous humor exceeds that of the draining fluid, which can permanently damage or even kill the optic nerve. This condition is called glaucoma.

People who are afflicted with this disease are generally unaware of the condition in the early stages. It goes unnoticed until it kills enough optic nerve cells to impair vision. Intraocular pressure has to be brought down and kept in the normal range to prevent glaucoma from spreading and causing further damage. This can be done with medication, eye drops or, in advanced stages, with surgery. Choosing the right therapy is paramount when treating glaucoma. To this end, the treating physician has to know the pressure level in the eye and its fluctuation over time.

Prevailing measurement methods are poorly suited to gather enough data so as to reveal meaningful insights. The main problem is that these measurements are usually taken in a doctor’s office, with too much time elapsing between sessions. Also, pressure can rise to harmfully high levels several times a day, so the likelihood of these readings going undetected is very high. This increases the risk of a physician opting for the wrong therapy many times over.

Easy to use, accurate results

Now scientists at Duisburg‘s Fraunhofer Institute for Microelectronic Circuits and Systems IMS have managed to solve this problem. “In a joint effort with Implandata Ophthalmic Products GmbH in Hanover, we developed EYEMATE, a microsensor system that enables patients to take contactless pressure measurements of their own eyes at any chosen frequency,” says Fraunhofer IMS’s Michael Görtz. A sensor implanted in the eye gauges pressure and temperature.

A hand-held reader records, digitizes and displays results; all the patient has to do is hold it in front of his or her eye. It takes the eye’s pressure and temperature readings in a matter of seconds – precisely, at any time and without touching the eye. With a data pool many times larger than what with conventional techniques can gather, attending physicians can apply the right therapy right away. The device’s readings can be downloaded, digitized and uploaded to cloud memory.

The attending physician can access patient data at any time to check and assess the disease’s progression and, if necessary, adjust the therapy on the spot. The patient no longer has to stop by the practice to this end. Patients may also access these data directly via a smartphone app, track their intraocular pressure readings and take the appropriate action if the pressure rising to alarming levels. The benefits increase with frequent application: the more often the patient uses the reader, the more meaningful the readings and the more personalized the therapy options.

Source: Fraunhofer Institute for Microelectronic Circuits and Systems IMS